PSMC6 anticorps (Regulatory Subunit)

N° du produit ABIN7142226

L’anticorps anti-PSMC6 Polyclonal Lapin est utilisé pour la détection de PSMC6 dans des échantillons de Humain. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour PSMC6 anticorps (Regulatory Subunit) (ABIN7142226)

Antigène: PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMC6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PSMC6 anticorps

Épitope: AA 1-260, Regulatory Subunit

Fonction: PSMC6 Antibody

Réactivité croisée: Souris, Rat

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human 26S proteasome regulatory subunit 10B protein (1-260AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PSMC6

Antigène: PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))

Autre désignation: PSMC6

Sujet:

Background: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.

Aliases: 26S protease regulatory subunit 10B antibody, 26S protease regulatory subunit S10B antibody, 26S proteasome AAA-ATPase subunit RPT4 antibody, CADP44 antibody, P44 antibody, Proteasome 26S subunit ATPase 6 antibody, Proteasome subunit p42 antibody, PRS10_HUMAN antibody, PSMC6 antibody, Rpt4 antibody, SUG2 antibody

UniProt: P62333

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway