ERI1 anticorps (AA 2-66) (FITC)
Aperçu rapide pour ERI1 anticorps (AA 2-66) (FITC) (ABIN7142341)
Antigène
Voir toutes ERI1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 2-66
-
Réactivité croisée
- Humain
-
Purification
- >95%, Protein G purified
-
Immunogène
- Recombinant Human 3\'-5\' exoribonuclease 1 protein (2-66AA)
-
Isotype
- IgG
-
-
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C,-80 °C
-
Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- ERI1 (Exoribonuclease 1 (ERI1))
-
Autre désignation
- ERI1
-
Sujet
-
Background: RNA exonuclease that binds to the 3\'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2\' and 3\'-hydroxyl groups at the last nucleotide of the histone 3\'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3\'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5\'-ACCCA-3\' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3\'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
Aliases: 3' 5' exonuclease ERI 1 antibody, 3' 5' exonuclease ERI1 antibody, 3' EXO antibody, 3' exoribonuclease antibody, 3' HEXO antibody, 3' histone mRNA exonuclease 1 antibody, 3''-5'' exonuclease eri1 antibody, 3''-5'' exoribonuclease 1 antibody, 3'EXO antibody, 3'HEXO antibody, ERI 1 antibody, Eri 1 homolog antibody, Eri-1 homolog antibody, eri1 antibody, Eri1 homolog antibody, ERI1_HUMAN antibody, HEXO antibody, Histone mRNA 3' end specific exonuclease antibody, Histone mRNA 3' end specific exoribonuclease antibody, Histone mRNA 3''-end-specific exoribonuclease antibody, Histone mRNA 3''-exonuclease 1 antibody, MGC35395 antibody, Protein 3''hExo antibody, THEX 1 antibody, THEX1 antibody, Three prime histone mRNA exonuclease 1 antibody
-
UniProt
- Q8IV48
Antigène
-