ERI1 anticorps (AA 2-66)

N° du produit ABIN7142343

L’anticorps Lapin Polyclonal anti-ERI1 a été validé pour WB, ELISA, IHC et IF. Il convient pour détecter ERI1 dans des échantillons de Humain.

Aperçu rapide pour ERI1 anticorps (AA 2-66) (ABIN7142343)

Antigène: ERI1 (Exoribonuclease 1 (ERI1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERI1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-ERI1 anticorps

Épitope: AA 2-66

Fonction: ERI1 Antibody

Réactivité croisée: Rat

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human 3\\\'-5\\\' exoribonuclease 1 protein (2-66AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ERI1

Antigène: ERI1 (Exoribonuclease 1 (ERI1))

Autre désignation: ERI1

Sujet:

Background: RNA exonuclease that binds to the 3\\\'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2\\\' and 3\\\'-hydroxyl groups at the last nucleotide of the histone 3\\\'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3\\\'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5\\\'-ACCCA-3\\\' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3\\\'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.

Aliases: 3' 5' exonuclease ERI 1 antibody, 3' 5' exonuclease ERI1 antibody, 3' EXO antibody, 3' exoribonuclease antibody, 3' HEXO antibody, 3' histone mRNA exonuclease 1 antibody, 3''-5'' exonuclease eri1 antibody, 3''-5'' exoribonuclease 1 antibody, 3'EXO antibody, 3'HEXO antibody, ERI 1 antibody, Eri 1 homolog antibody, Eri-1 homolog antibody, eri1 antibody, Eri1 homolog antibody, ERI1_HUMAN antibody, HEXO antibody, Histone mRNA 3' end specific exonuclease antibody, Histone mRNA 3' end specific exoribonuclease antibody, Histone mRNA 3''-end-specific exoribonuclease antibody, Histone mRNA 3''-exonuclease 1 antibody, MGC35395 antibody, Protein 3''hExo antibody, THEX 1 antibody, THEX1 antibody, Three prime histone mRNA exonuclease 1 antibody

UniProt: Q8IV48