RPL13A anticorps (AA 63-190) (FITC)

N° du produit ABIN7142746

Cet anticorps anti-RPL13A est un anticorps Lapin Polyclonal détectant RPL13A dans . Adapté pour Humain.

Aperçu rapide pour RPL13A anticorps (AA 63-190) (FITC) (ABIN7142746)

Antigène: RPL13A (Ribosomal Protein L13a (RPL13A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPL13A est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Détail du produit anti-RPL13A anticorps (FITC)

Épitope: AA 63-190

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human 60S ribosomal protein L13a protein (63-190AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RPL13A

Antigène: RPL13A (Ribosomal Protein L13a (RPL13A))

Autre désignation: RPL13A

Sujet:

Background: Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3\'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA.

Aliases: RPL13A antibody, 60S ribosomal protein L13a antibody, 23 kDa highly basic protein antibody, Large ribosomal subunit protein uL13 antibody

UniProt: P40429