ADCY6 anticorps (AA 9-118) (HRP)

N° du produit ABIN7143337

Cet anticorps anti-ADCY6 est un anticorps Lapin Polyclonal détectant ADCY6 dans ELISA. Adapté pour Humain.

Aperçu rapide pour ADCY6 anticorps (AA 9-118) (HRP) (ABIN7143337)

Antigène: ADCY6 (Adenylate Cyclase 6 (ADCY6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADCY6 est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-ADCY6 anticorps (HRP)

Épitope: AA 9-118

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Adenylate cyclase type 6 protein (9-118AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ADCY6

Antigène: ADCY6 (Adenylate Cyclase 6 (ADCY6))

Autre désignation: ADCY6

Sujet:

Background: Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors (PubMed:17916776, PubMed:17110384). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells (PubMed:17916776). Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption. Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion. Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion (By similarity). Signaling mediates cAMP-dependent activation of protein kinase PKA. This promotes increased phosphorylation of various proteins, including AKT. Plays a role in regulating cardiac sarcoplasmic reticulum Ca(2+) uptake and storage, and is required for normal heart ventricular contractibility. May contribute to normal heart function (By similarity). Mediates vasodilatation after activation of beta-adrenergic receptors by isoproterenol (PubMed:17916776). Contributes to bone cell responses to mechanical stimuli (By similarity).

Aliases: AC6 antibody, ACVI antibody, ADCY 6 antibody, Adcy6 antibody, ADCY6_HUMAN antibody, ADCYB antibody, Adenylate cyclase 6 antibody, Adenylate cyclase type 6 antibody, Adenylate cyclase type VI antibody, Adenylyl cyclase 6 antibody, ATP pyrophosphate lyase 6 antibody, ATP pyrophosphate-lyase 6 antibody, Ca(2+) inhibitable adenylyl cyclase antibody, Ca(2+)-inhibitable adenylyl cyclase antibody, DKFZp779F075 antibody, EC 4.6.1.1 antibody, KIAA0422 antibody

UniProt: O43306

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma