SSX2IP anticorps (AA 485-614)

N° du produit ABIN7143574

Cet anticorps anti-SSX2IP est un anticorps Lapin Polyclonal détectant SSX2IP dans ELISA, WB, IHC et IF. Adapté pour Humain.

Aperçu rapide pour SSX2IP anticorps (AA 485-614) (ABIN7143574)

Antigène: SSX2IP (Synovial Sarcoma, X Breakpoint 2 Interacting Protein (SSX2IP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SSX2IP est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-SSX2IP anticorps

Épitope: AA 485-614

Réactivité croisée: Humain, Rat

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Afadin- and alpha-actinin-binding protein (485-614AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SSX2IP

Antigène: SSX2IP (Synovial Sarcoma, X Breakpoint 2 Interacting Protein (SSX2IP))

Autre désignation: SSX2IP

Sujet:

Background: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling (By similarity). Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73, the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome (PubMed:23816619, PubMed:26545777). Involved in ciliogenesis (PubMed:24356449). It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia (PubMed:24356449).

Aliases: ADIP antibody, ADIP_HUMAN antibody, Afadin and alpha actinin binding protein antibody, Afadin DIL domain interacting protein antibody, Afadin DIL domain-interacting protein antibody, Afadin- and alpha-actinin-binding protein antibody, FLJ10848 antibody, KIAA0923 antibody, MGC75026 antibody, OTTHUMP00000011574 antibody, SSX 2 interacting protein antibody, SSX2 interacting protein antibody, SSX2-interacting protein antibody, SSX2IP antibody, Synovial sarcoma X breakpoint 2 interacting protein antibody

UniProt: Q9Y2D8