Chromosome 6 Open Reading Frame 134 (C6orf134) (AA 194-238) anticorps (Biotin)

N° du produit ABIN7143949

Cet anticorps anti- est un anticorps Lapin Polyclonal détectant dans ELISA. Adapté pour Humain.

Aperçu rapide pour Chromosome 6 Open Reading Frame 134 (C6orf134) (AA 194-238) anticorps (Biotin) (ABIN7143949)

Antigène: Chromosome 6 Open Reading Frame 134 (C6orf134)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Biotin

Application: ELISA

Détail du produit

Épitope: AA 194-238

Fonction: ATAT1 Antibody, Biotin conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Alpha-tubulin N-acetyltransferase 1 protein (194-238AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détail du antigène

Antigène: Chromosome 6 Open Reading Frame 134 (C6orf134)

Autre désignation: ATAT1

Sujet:

Background: Specifically acetylates \'Lys-40\' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics, this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.

Aliases: Acetyltransferase mec 17 homolog antibody, Acetyltransferase mec-17 homolog antibody, Alpha TAT antibody, Alpha tubulin acetyltransferase 1 antibody, Alpha tubulin N acetyltransferase antibody, Alpha-TAT antibody, Alpha-tubulin N-acetyltransferase antibody, ATAT_HUMAN antibody, ATAT1 antibody, Chromosome 6 open reading frame 134 antibody, Hypothetical protein LOC79969 antibody, MEC17 antibody, Nbla00487 antibody, TAT antibody

UniProt: Q5SQI0