CD13 anticorps (AA 34-219)

N° du produit ABIN7144005

L’anticorps Lapin Polyclonal anti-CD13 a été validé pour WB, IHC, ELISA et IF. Il convient pour détecter CD13 dans des échantillons de Humain.

Aperçu rapide pour CD13 anticorps (AA 34-219) (ABIN7144005)

Antigène: CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD13 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-CD13 anticorps

Épitope: AA 34-219

Fonction: ANPEP Antibody

Réactivité croisée: Souris

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Aminopeptidase N protein (34-219AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CD13

Antigène: CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

Autre désignation: ANPEP

Sujet:

Background: Broad specificity aminopeptidase. Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. May play a critical role in the pathogenesis of cholesterol gallstone disease. May be involved in the metabolism of regulatory peptides of diverse cell types, responsible for the processing of peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. Found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells and to degrade neurotransmitters at synaptic junctions. Is also implicated as a regulator of IL-8 bioavailability in the endometrium, and therefore may contribute to the regulation of angiogenesis. Is used as a marker for acute myeloid leukemia and plays a role in tumor invasion. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein. Mediates as well human cytomegalovirus (HCMV) infection.

Aliases: Alanyl (membrane) aminopeptidase antibody, Alanyl aminopeptidase antibody, Aminopeptidase M antibody, Aminopeptidase N antibody, AMPN_HUMAN antibody, ANPEP antibody, AP M antibody, AP N antibody, AP-M antibody, AP-N antibody, APN antibody, CD 13 antibody, CD13 antibody, CD13 antigen antibody, gp150 antibody, hAPN antibody, LAP 1 antibody, LAP1 antibody, Microsomal aminopeptidase antibody, Myeloid plasma membrane glycoprotein CD13 antibody, p150 antibody, PEPN antibody

UniProt: P15144

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones