ANGPTL4 anticorps (AA 26-406)

N° du produit ABIN7144120

Cet anticorps anti-ANGPTL4 est un anticorps Lapin Polyclonal détectant ANGPTL4 dans IHC et ELISA. Adapté pour Humain.

Aperçu rapide pour ANGPTL4 anticorps (AA 26-406) (ABIN7144120)

Antigène: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANGPTL4 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-ANGPTL4 anticorps

Épitope: AA 26-406

Fonction: ANGPTL4 Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Angiopoietin-related protein 4 protein (26-406AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ANGPTL4

Antigène: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Autre désignation: ANGPTL4

Sujet:

Background: Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.

Aliases: Angiopoietin like 4 antibody, Angiopoietin related protein 4 antibody, Angiopoietin-like protein 4 antibody, Angiopoietin-related protein 4 antibody, ANGL4_HUMAN antibody, ANGPT L2 antibody, ANGPT L4 antibody, ANGPTL2 antibody, Angptl4 antibody, ARP4 antibody, Fasting induced adipose factor antibody, FIAF antibody, HARP antibody, Hepatic angiopoietin related protein antibody, Hepatic fibrinogen/angiopoietin related protein antibody, Hepatic fibrinogen/angiopoietin-related protein antibody, HFARP antibody, NL2 antibody, Peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin related protein antibody, PGAR antibody, pp1158 antibody, PPARG angiopoietin related protein antibody, PSEC0166 antibody, TGQTL antibody, UNQ171 antibody, Weakly similar to angiopoietin 1 [H.sapiens] antibody

UniProt: Q9BY76

Pathways: Regulation of Lipid Metabolism by PPARalpha