Aurora Kinase C anticorps (AA 12-143)

N° du produit ABIN7145083

Détail du produit anti-Aurora Kinase C anticorps

Antigène: Aurora Kinase C (AURKC)

Épitope: AA 12-143

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aurora Kinase C est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Aurora kinase C protein (12-143AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Aurora Kinase C

Antigène: Aurora Kinase C (AURKC)

Autre désignation: AURKC (AURKC Produits)

Synonymes: anticorps AURKC, anticorps AIE2, anticorps AIK3, anticorps ARK3, anticorps AurC, anticorps SPGF5, anticorps STK13, anticorps aurora-C, anticorps AIE1, anticorps ARK-3, anticorps IAK3, anticorps Stk13, anticorps aurora kinase C, anticorps AURKC, anticorps Aurkc

Sujet:

Background: Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at \\\'Ser-10\\\' and \\\'Ser-28\\\'. AURKC phosphorylates the CPC complex subunits BIRC5/survivin and INCENP leading to increased AURKC activity. Phosphorylates TACC1, another protein involved in cell division, at \\\'Ser-228\\\'.

Aliases: AURKC antibody, AIE 2 antibody, Aie1 antibody, AIE2 antibody, AIK 3 antibody, AIK3 antibody, ARK 3 antibody, ARK-3 antibody, ARK3 antibody, Aur C antibody, AurC antibody, Aurkc antibody, AURKC_HUMAN antibody, aurora 3 antibody, Aurora C antibody, Aurora kinase C antibody, aurora related kinase 3 antibody, Aurora-related kinase 3 antibody, Aurora/Ipl1 related kinase 3 antibody, Aurora/Ipl1-related kinase 3 antibody, Aurora/Ipl1/Eg2 protein 2 antibody, EC 2.7.11.1 antibody, Serine threonine protein kinase 13 antibody, serine/threonine kinase 13 (aurora/IPL1 like) antibody, serine/threonine protein kinase aurora C antibody, Serine/threonine-protein kinase 13 antibody, Serine/threonine-protein kinase aurora-C antibody, SPGF5 antibody, STK13 antibody

UniProt: Q9UQB9

Pathways: Cycle Cellulaire, Maintenance of Protein Location