CD79a anticorps (AA 70-142)

N° du produit ABIN7145141

Détail du produit anti-CD79a anticorps

Antigène: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Épitope: AA 70-142

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD79a est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human B-cell antigen receptor complex-associated protein alpha chain protein (70-142AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CD79a

Antigène: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Autre désignation: CD79A (CD79A Produits)

Synonymes: anticorps CD79A, anticorps Ig-alpha, anticorps Iga, anticorps Igalpha, anticorps Ly-54, anticorps Ly54, anticorps mb-1, anticorps IGA, anticorps MB-1, anticorps IG-alpha, anticorps CD79a molecule, anticorps CD79A antigen (immunoglobulin-associated alpha), anticorps Cd79a molecule-like, anticorps CD79A, anticorps Cd79a, anticorps Cd79al

Sujet:

Background: Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.

Aliases: B lymphocyte-specific MB1 protein antibody, B-cell antigen receptor complex-associated protein alpha chain antibody, CD 79a antibody, CD79a antibody, CD79a antigen (immunoglobulin-associated alpha) antibody, CD79A antigen antibody, CD79a molecule, immunoglobulin-associated alpha antibody, CD79A_HUMAN antibody, Ig alpha antibody, Ig-alpha antibody, IGA antibody, IgM-alpha antibody, Immunoglobulin-associated alpha antibody, Ly54 antibody, MB-1 membrane glycoprotein antibody, MB1 antibody, Membrane-bound immunoglobulin-associated protein antibody, Surface IgM-associated protein antibody

UniProt: P11912

Pathways: BCR Signaling