BNIP3L/NIX anticorps (AA 1-187)

N° du produit ABIN7145332

Cet anticorps anti-BNIP3L/NIX est un anticorps Lapin Polyclonal détectant BNIP3L/NIX dans IHC et ELISA. Adapté pour Humain.

Aperçu rapide pour BNIP3L/NIX anticorps (AA 1-187) (ABIN7145332)

Antigène: BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BNIP3L/NIX est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-BNIP3L/NIX anticorps

Épitope: AA 1-187

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like protein (1-187AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur BNIP3L/NIX

Antigène: BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

Autre désignation: BNIP3L

Sujet:

Background: Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.

Aliases: Adenovirus E1B19k binding protein B5 antibody, Adenovirus E1B19K-binding protein B5 antibody, BCL2/adenovirus E1B 19 kd protein interacting protein 3a antibody, BCL2/adenovirus E1B 19 kDa protein interacting protein 3A antibody, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like antibody, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A antibody, BCL2/adenovirus E1B 19 kDa interacting protein 3 like antibody, BNI3L_HUMAN antibody, BNIP3a antibody, BNIP3H antibody, BNIP3L antibody, BNIP3L protein antibody, NIP3 like protein X antibody, NIP3-like protein X antibody, NIP3L antibody, NIX antibody

UniProt: O60238

Pathways: Autophagy