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ATG14 anticorps (AA 1-492)

ATG14 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7145339
  • Antigène Voir toutes ATG14 Anticorps
    ATG14 (ATG14 Autophagy Related 14 (ATG14))
    Épitope
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-492
    Reactivité
    • 46
    • 15
    • 8
    • 1
    Humain
    Hôte
    • 38
    • 8
    Lapin
    Clonalité
    • 38
    • 8
    Polyclonal
    Conjugué
    • 18
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp ATG14 est non-conjugé
    Application
    • 26
    • 21
    • 17
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Beclin 1-associated autophagy-related key regulator protein (1-492AA)
    Isotype
    IgG
    Top Product
    Discover our top product ATG14 Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:200-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    ATG14 (ATG14 Autophagy Related 14 (ATG14))
    Autre désignation
    ATG14 (ATG14 Produits)
    Synonymes
    anticorps ATG14L, anticorps BARKOR, anticorps KIAA0831, anticorps 4832427M01, anticorps Atg14L, anticorps D14Ertd114e, anticorps D14Ertd436e, anticorps RGD1304610, anticorps autophagy related 14, anticorps ATG14, anticorps Atg14
    Sujet

    Background: Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (PubMed:18843052, PubMed:19050071). Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine (PubMed:19270696, PubMed:20713597). Promotes BECN1 translocation from the trans-Golgi network to autophagosomes (PubMed:20713597). Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (PubMed:23878393). Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK (PubMed:23878393). Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion (PubMed:25686604). Modulates the hepatic lipid metabolism (By similarity).

    Aliases: 4832427M01 antibody, ATG14 antibody, Atg14L antibody, Autophagy-related protein 14-like protein antibody, BAKOR_HUMAN antibody, Barkor antibody, Beclin 1-associated autophagy-related key regulator antibody, D14Ertd114e antibody, D14Ertd436e antibody, KIAA0831 antibody, mCG_6911 antibody

    UniProt
    Q6ZNE5
    Pathways
    Autophagy
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