BMP10 anticorps (AA 317-424)

N° du produit ABIN7145679

L’anticorps Lapin Polyclonal anti-BMP10 a été validé pour IHC et ELISA. Il convient pour détecter BMP10 dans des échantillons de Humain.

Aperçu rapide pour BMP10 anticorps (AA 317-424) (ABIN7145679)

Antigène: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMP10 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-BMP10 anticorps

Épitope: AA 317-424

Fonction: BMP10 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Bone morphogenetic protein 10 protein (317-424AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur BMP10

Antigène: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Autre désignation: BMP10

Sujet:

Background: Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

Aliases: BMP-10 antibody, Bmp10 antibody, BMP10_HUMAN antibody, Bone morphogenetic protein 10 antibody, Bone morphogenetic protein 10 preproprotein antibody, MGC126783 antibody, OTTHUMP00000159973 antibody

UniProt: O95393

Pathways: Hormone Activity, Regulation of Muscle Cell Differentiation