CHMP1B anticorps (AA 1-199)

N° du produit ABIN7147518

L’anticorps Lapin Polyclonal anti-CHMP1B a été validé pour IHC et ELISA. Il convient pour détecter CHMP1B dans des échantillons de Humain.

Aperçu rapide pour CHMP1B anticorps (AA 1-199) (ABIN7147518)

Antigène: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHMP1B est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-CHMP1B anticorps

Épitope: AA 1-199

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Charged multivesicular body protein 1b protein (1-199AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CHMP1B

Antigène: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Autre désignation: CHMP1B

Sujet:

Background: Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B and SPAST to the midbody of dividing cells. Involved in HIV-1 p6- and p9-dependent virus release.

Aliases: CHMP1B antibody, C18orf2Charged multivesicular body protein 1b antibody, CHMP1.5 antibody, Chromatin-modifying protein 1b antibody, CHMP1b antibody, Vacuolar protein sorting-associated protein 46-2 antibody, Vps46-2 antibody, hVps46-2 antibody

UniProt: Q7LBR1