CBX3 anticorps (AA 10-122)
Aperçu rapide pour CBX3 anticorps (AA 10-122) (ABIN7147701)
Antigène
Voir toutes CBX3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 10-122
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human Chromobox protein homolog 3 protein (10-122AA)
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Isotype
- IgG
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Indications d'application
- Recommended dilution: IF:1:50-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CBX3 (Chromobox Homolog 3 (CBX3))
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Autre désignation
- CBX3
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Sujet
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Background: Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at \'Lys-9\', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 \'Lys-9\' trimethylation, mediates the recruitment of the methyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1.
Aliases: CBX 3 antibody, CBX3 antibody, CBX3_HUMAN antibody, Chromobox homolog 3 (HP1 gamma homolog, Drosophila) antibody, Chromobox homolog 3 antibody, Chromobox protein homolog 3 antibody, GAMMA antibody, HECH antibody, Heterochromatin like protein 1 antibody, Heterochromatin protein 1 homolog gamma antibody, Heterochromatin protein HP1 gamma antibody, HP1 gamma antibody, HP1 gamma homolog antibody, HP1Hs gamma antibody, Modifier 2 protein antibody
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UniProt
- Q13185
Antigène
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