Cofilin anticorps (AA 4-144)

N° du produit ABIN7148044

Détail du produit anti-Cofilin anticorps

Antigène: Cofilin (CFL1) (Cofilin 1 (CFL1))

Épitope: AA 4-144

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cofilin est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Cofilin-1 protein (4-144AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Cofilin

Antigène: Cofilin (CFL1) (Cofilin 1 (CFL1))

Autre désignation: CFL1 (CFL1 Produits)

Synonymes: anticorps cfl1, anticorps xac1, anticorps xac2, anticorps cfl, anticorps cb86, anticorps sb:cb86, anticorps zgc:56501, anticorps wu:fb18a04, anticorps wu:fk77b03, anticorps 12/8, anticorps ADF, anticorps ADF/cofilin, anticorps Adf, anticorps CG4254, anticorps Cadf, anticorps D-cof, anticorps D61, anticorps Dmel\\CG4254, anticorps T8, anticorps Tsr, anticorps cofilin, anticorps cofilin/ADF, anticorps cofilin/actin depolymerizing factor homolog, anticorps l(2)03101, anticorps l(2)k03101, anticorps l(2)k05633, anticorps l(2)k13409, anticorps ntf, anticorps CFL, anticorps AA959946, anticorps Cof, anticorps CFL1, anticorps cofilin 1 (non-muscle) L homeolog, anticorps cofilin 1 (non-muscle), anticorps cofilin 1 (non-muscle), like, anticorps cofilin 1, anticorps twinstar, anticorps cofilin, anticorps cofilin 1, non-muscle, anticorps Contrafreeloading, anticorps cfl1.L, anticorps cfl1, anticorps cfl1l, anticorps CFL1, anticorps tsr, anticorps COF1, anticorps TSTA_042790, anticorps Cfl1, anticorps CFL

Sujet:

Background: Binds to F-actin and exhibits pH -sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed:11812157, PubMed:15580268, PubMed:21834987, PubMed:23633677). Required for neural tube morphogenesis and neural crest cell migration (By similarity).

Aliases: 18 kDa phosphoprotein antibody, CFL 1 antibody, CFL antibody, CFL1 antibody, COF1_HUMAN antibody, Cofilin 1 antibody, Cofilin 1 non muscle antibody, Cofilin antibody, Cofilin non muscle isoform antibody, Cofilin-1 antibody, epididymis secretory protein Li 15 antibody, HEL-S-15 antibody, non-muscle isoform antibody, p18 antibody

UniProt: P23528

Pathways: Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events