GPS1 anticorps (AA 222-491)

N° du produit ABIN7148491

Cet anticorps anti-GPS1 est un anticorps Lapin Polyclonal détectant GPS1 dans WB, IHC et ELISA. Adapté pour Humain.

Aperçu rapide pour GPS1 anticorps (AA 222-491) (ABIN7148491)

Antigène: GPS1 (G Protein Pathway Suppressor 1 (GPS1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-GPS1 anticorps

Épitope: AA 222-491

Fonction: GPS1 Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human COP9 signalosome complex subunit 1 protein (222-491AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GPS1

Antigène: GPS1 (G Protein Pathway Suppressor 1 (GPS1))

Autre désignation: GPS1

Sujet:

Background: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction.

Aliases: COP9 signalosome complex subunit 1 antibody, COP9 signalosome subunit 1 antibody, COPS1 antibody, CSN 1 antibody, CSN1_HUMAN antibody, FUS6/COP11, Arabidopsis, homolog of antibody, G protein pathway suppressor 1 antibody, GPS-1 antibody, Gps1 antibody, JAB1-containing signalosome subunit 1 antibody, Protein GPS1 antibody, Protein MFH antibody, SGN1 antibody, Signalosome subunit 1 antibody

UniProt: Q13098

Pathways: Cycle Cellulaire