GPS1 anticorps (AA 222-491)

N° du produit ABIN7148491

Détail du produit anti-GPS1 anticorps

Antigène: GPS1 (G Protein Pathway Suppressor 1 (GPS1))

Épitope: AA 222-491

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPS1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human COP9 signalosome complex subunit 1 protein (222-491AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GPS1

Antigène: GPS1 (G Protein Pathway Suppressor 1 (GPS1))

Autre désignation: GPS1 (GPS1 Produits)

Synonymes: anticorps COPS1, anticorps CSN1, anticorps Cops1, anticorps Csn1, anticorps R75577, anticorps Sgn1, anticorps im:6909260, anticorps im:7145572, anticorps zgc:154082, anticorps csn1, anticorps ARABIDOPSIS THALIANA FUSCA 6, anticorps ATFUS6, anticorps ATSK31, anticorps CONSTITUTIVE PHOTOMORPHOGENIC 11, anticorps COP11, anticorps COP9 SIGNALOSOME SUBUNIT 1, anticorps EMB78, anticorps EMBRYO DEFECTIVE 78, anticorps FUSCA 6, anticorps SHAGGY-LIKE KINASE 31, anticorps SK31, anticorps G protein pathway suppressor 1, anticorps casein alpha s1, anticorps G protein pathway suppressor 1 L homeolog, anticorps COP9 signalosome complex subunit 1, anticorps GPS1, anticorps CSN1S1, anticorps LOC693104, anticorps CC1G_07518, anticorps Bm1_55055, anticorps Gps1, anticorps gps1, anticorps gps1.L, anticorps FUS6, anticorps csn-1

Sujet:

Background: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction.

Aliases: COP9 signalosome complex subunit 1 antibody, COP9 signalosome subunit 1 antibody, COPS1 antibody, CSN 1 antibody, CSN1_HUMAN antibody, FUS6/COP11, Arabidopsis, homolog of antibody, G protein pathway suppressor 1 antibody, GPS-1 antibody, Gps1 antibody, JAB1-containing signalosome subunit 1 antibody, Protein GPS1 antibody, Protein MFH antibody, SGN1 antibody, Signalosome subunit 1 antibody

UniProt: Q13098

Pathways: Cycle Cellulaire