Coxsackie Adenovirus Receptor anticorps (AA 259-365) (HRP)

N° du produit ABIN7148652

L’anticorps Lapin Polyclonal anti-Coxsackie Adenovirus Receptor a été validé pour ELISA. Il convient pour détecter Coxsackie Adenovirus Receptor dans des échantillons de Humain.

Aperçu rapide pour Coxsackie Adenovirus Receptor anticorps (AA 259-365) (HRP) (ABIN7148652)

Antigène: Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Coxsackie Adenovirus Receptor est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-Coxsackie Adenovirus Receptor anticorps (HRP)

Épitope: AA 259-365

Fonction: CXADR Antibody, HRP conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Coxsackievirus and adenovirus receptor protein (259-365AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Coxsackie Adenovirus Receptor

Antigène: Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))

Autre désignation: CXADR

Sujet:

Background: Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.

Aliases: 46 kD coxsackievirus and adenovirus receptor CAR protein antibody, 46 kD coxsackievirus and adenovirus receptor protein antibody, CAR antibody, CAR4/6 antibody, Coxsackie virus and adenovirus receptor antibody, Coxsackie virus B receptor antibody, Coxsackievirus and adenovirus receptor antibody, Coxsackievirus B adenovirus receptor antibody, Coxsackievirus B-adenovirus receptor antibody, CVB3 binding protein antibody, CVB3-binding protein antibody, Cxadr antibody, CXADR Ig like cell adhesion molecule antibody, CXAR_HUMAN antibody, hCAR antibody, HCVADR antibody

UniProt: P78310

Pathways: Cell-Cell Junction Organization