CBP anticorps (AA 2217-2442) (Biotin)

N° du produit ABIN7148672

Cet anticorps Lapin Polyclonal détecte spécifiquement CBP dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour CBP anticorps (AA 2217-2442) (Biotin) (ABIN7148672)

Antigène: CBP (CREBBP) (CREB Binding Protein (CREBBP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBP est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-CBP anticorps (Biotin)

Épitope: AA 2217-2442

Fonction: CREBBP Antibody, Biotin conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human CREB-binding protein (2217-2442AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CBP

Antigène: CBP (CREBBP) (CREB Binding Protein (CREBBP))

Autre désignation: CREBBP

Sujet:

Background: Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA, acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) (PubMed:24939902).

Aliases: CBP antibody, CBP_HUMAN antibody, CREB binding protein antibody, CREB-binding protein antibody, Crebbp antibody, Cyclic AMP responsive enhancer binding protein antibody, KAT3A antibody, RSTS antibody, RTS antibody, Rubinstein Taybi syndrome antibody

UniProt: Q92793

Pathways: TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha