CDK3 anticorps (AA 220-297)

N° du produit ABIN7148881

Cet anticorps anti-CDK3 est un anticorps Lapin Polyclonal détectant CDK3 dans ELISA et IHC. Adapté pour Humain.

Aperçu rapide pour CDK3 anticorps (AA 220-297) (ABIN7148881)

Antigène: CDK3 (Cyclin-Dependent Kinase 3 (CDK3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-CDK3 anticorps

Épitope: AA 220-297

Fonction: CDK3 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Cyclin-dependent kinase 3 protein (220-297AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CDK3

Antigène: CDK3 (Cyclin-Dependent Kinase 3 (CDK3))

Autre désignation: CDK3

Sujet:

Background: Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle, involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner.

Aliases: Cdk 3 antibody, Cdk3 antibody, CDK3_HUMAN antibody, CDKN3 antibody, Cell division kinase 3 antibody, Cell division protein kinase 3 antibody, Cyclin dependent kinase 3 antibody, Cyclin-dependent kinase 3 antibody, OTTHUMP00000206828 antibody, p36 antibody

UniProt: Q00526

Pathways: Cycle Cellulaire