Cyclin H anticorps (AA 261-319)

N° du produit ABIN7148939

Détail du produit anti-Cyclin H anticorps

Antigène: Cyclin H (CCNH)

Épitope: AA 261-319

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin H est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris, Rat

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Cyclin-H protein (261-319AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Cyclin H

Antigène: Cyclin H (CCNH)

Autre désignation: CCNH (CCNH Produits)

Synonymes: anticorps zgc:114132, anticorps cak, anticorps p34, anticorps p37, anticorps Cych, anticorps ACYPI004637, anticorps ccnh, anticorps Cyclin-H, anticorps 142767_at, anticorps CG7405, anticorps Dmel\\CG7405, anticorps CAK, anticorps 6330408H09Rik, anticorps AI661354, anticorps AV102684, anticorps AW538719, anticorps ccnh-A, anticorps cyclin H, anticorps cyclin-H, anticorps Cyclin H, anticorps CYclin H, anticorps cyclin H L homeolog, anticorps CCNH, anticorps ccnh, anticorps LOC5577539, anticorps Cych, anticorps CycH, anticorps cyh-1, anticorps Ccnh, anticorps ccnh.L

Sujet:

Background: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

Aliases: 6330408H09Rik antibody, AI661354 antibody, AV102684 antibody, AW538719 antibody, CAK antibody, CAK complex subunit antibody, ccnh antibody, CCNH_HUMAN antibody, CDK activating kinase antibody, CDK activating kinase complex subunit antibody, Cyclin dependent kinase activating kinase antibody, cyclin dependent kinase activating kinase complex subunit antibody, Cyclin H antibody, Cyclin-H antibody, CyclinH antibody, MO15 associated protein antibody, MO15-associated protein antibody, p34 antibody, p36 antibody, p37 antibody

UniProt: P51946

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, M Phase