CPEB4 anticorps (AA 244-515) (HRP)

N° du produit ABIN7149351

L’anticorps Lapin Polyclonal anti-CPEB4 a été validé pour ELISA. Il convient pour détecter CPEB4 dans des échantillons de Humain.

Aperçu rapide pour CPEB4 anticorps (AA 244-515) (HRP) (ABIN7149351)

Antigène: CPEB4 (Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CPEB4 est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-CPEB4 anticorps (HRP)

Épitope: AA 244-515

Fonction: CPEB4 Antibody, HRP conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Cytoplasmic polyadenylation element-binding protein 4 protein (244-515AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CPEB4

Antigène: CPEB4 (Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4))

Autre désignation: CPEB4

Sujet:

Background: Sequence-specific RNA-binding protein that binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5\\\'-UUUUUAU-3\\\') within the mRNA 3\\\'-UTR (PubMed:24990967). RNA binding results in a clear conformational change analogous to the Venus fly trap mechanism (PubMed:24990967). Regulates activation of unfolded protein response (UPR) in the process of adaptation to ER stress in liver, by maintaining translation of CPE-regulated mRNAs in conditions in which global protein synthesis is inhibited (By similarity). Required for cell cycle progression, specifically for cytokinesis and chromosomal segregation (PubMed:26398195). Plays a role as an oncogene promoting tumor growth and progression by positively regulating translation of t-plasminogen activator/PLAT (PubMed:22138752). Stimulates proliferation of melanocytes (PubMed:27857118). In contrast to CPEB1 and CPEB3, does not play role in synaptic plasticity, learning and memory (By similarity).

Aliases: CPE binding protein 4 antibody, CPE-binding protein 4 antibody, CPE-BP4 antibody, cpeb4 antibody, CPEB4_HUMAN antibody, Cytoplasmic polyadenylation element binding protein 4 antibody, Cytoplasmic polyadenylation element-binding protein 4 antibody, hCPEB-4 antibody, KIAA1673 antibody

UniProt: Q17RY0