Nitrilase 1 anticorps (AA 1-243) (Biotin)
Aperçu rapide pour Nitrilase 1 anticorps (AA 1-243) (Biotin) (ABIN7149535)
Antigène
Voir toutes Nitrilase 1 (NIT1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-243
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human Deaminated glutathione amidase protein (1-243AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Nitrilase 1 (NIT1)
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Autre désignation
- NIT1
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Sujet
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Background: Catalyzes the hydrolysis of the amide bond in N-(4-oxoglutarate)-L-cysteinylglycine (deaminated glutathione), a metabolite repair reaction to dispose of the harmful deaminated glutathione. Plays a role in cell growth and apoptosis: loss of expression promotes cell growth, resistance to DNA damage stress and increased incidence to NMBA-induced tumors. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells, this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells.
Aliases: MGC57670 antibody, NIT1 antibody, NIT1_HUMAN antibody, Nitrilase 1 antibody, Nitrilase homolog 1 antibody
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UniProt
- Q86X76
Antigène
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