DAPK2 anticorps (AA 222-370)

N° du produit ABIN7149554

Cet anticorps Lapin Polyclonal détecte spécifiquement DAPK2 dans WB, ELISA, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour DAPK2 anticorps (AA 222-370) (ABIN7149554)

Antigène: DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DAPK2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-DAPK2 anticorps

Épitope: AA 222-370

Fonction: DAPK2 Antibody

Réactivité croisée: Souris

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Death-associated protein kinase 2 protein (222-370AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DAPK2

Antigène: DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))

Autre désignation: DAPK2

Sujet:

Background: Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation. Isoform 2 is not regulated by calmodulin. It can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death.

Aliases: DAK2 antibody, DAP kinase 2 antibody, DAP kinase related protein 1 antibody, DAP kinase related protein 1 beta isoform antibody, DAP-kinase-related protein 1 antibody, DAPK2 antibody, DAPK2_HUMAN antibody, Death associated protein kinase 2 antibody, Death-associated protein kinase 2 antibody, DRP 1 antibody, DRP-1 antibody, DRP1 antibody, MGC119312 antibody

UniProt: Q9UIK4