DOCK7 anticorps (AA 1440-1671) (FITC)
Aperçu rapide pour DOCK7 anticorps (AA 1440-1671) (FITC) (ABIN7149601)
Antigène
Voir toutes DOCK7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1440-1671
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human Dedicator of cytokinesis protein 7 protein (1440-1671AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))
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Autre désignation
- DOCK7
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Sujet
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Background: Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 \\\'Ser-15\\\' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation, negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).
Aliases: DOCK7 antibody, KIAA1771Dedicator of cytokinesis protein 7 antibody
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UniProt
- Q96N67
Antigène
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