DKK4 anticorps (AA 19-224)

N° du produit ABIN7149890

Détail du produit anti-DKK4 anticorps

Antigène: DKK4 (Dickkopf Homolog 4 (Xenopus Laevis) (DKK4))

Épitope: AA 19-224

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DKK4 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Dickkopf-related protein 4 protein (19-224AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DKK4

Antigène: DKK4 (Dickkopf Homolog 4 (Xenopus Laevis) (DKK4))

Autre désignation: DKK4 (DKK4 Produits)

Synonymes: anticorps DKK-4, anticorps Dkk-4, anticorps RGD1563172, anticorps dickkopf WNT signaling pathway inhibitor 4, anticorps DKK4, anticorps Dkk4

Sujet:

Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

Aliases: Dickkopf 4 antibody, Dickkopf gene 4 antibody, Dickkopf homolog 4 (Xenopus laevis) antibody, Dickkopf homolog 4 antibody, Dickkopf related protein 4 antibody, Dickkopf-4 antibody, Dickkopf-related protein 4 short form antibody, Dickkopf4 antibody, DKK 4 antibody, Dkk-4 antibody, DKK4 antibody, DKK4_HUMAN antibody, hDkk 4 antibody, hDkk-4 antibody, hDkk4 antibody, MGC129562 antibody, MGC129563 antibody

UniProt: Q9UBT3

Pathways: Signalisation WNT