Neurofibromin 1 anticorps (pSer2515) (Biotin)

N° du produit ABIN710773

Cet anticorps Lapin Polyclonal détecte spécifiquement Neurofibromin 1 dans ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Neurofibromin 1 anticorps (pSer2515) (Biotin) (ABIN710773)

Antigène: Neurofibromin 1 (NF1)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurofibromin 1 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Neurofibromin 1 anticorps (Biotin)

Épitope: pSer2515

Réactivité croisée: Humain, Souris

Homologie: Rat,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human NF1 around the phosphorylation site of Ser2515

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Neurofibromin 1

Antigène: Neurofibromin 1 (NF1)

Autre désignation: NF1

Sujet:

Synonyms: NF1phospho S2515, p-NF1S2515, DKFZp686J1293, FLJ21220, Neurofibromatosis Noonan syndrome, Neurofibromatosis related protein NF 1, Neurofibromatosis related protein NF1, neurofibromatosis type I, Neurofibromatosis-related protein NF-1, Neurofibromin 1, Neurofibromin truncated, Neurofibromin1, NF 1, NF, NF1, NF1_HUMAN, NFNS, Type 1 Neurofibromatosis, von Recklinghausen disease neurofibromin, von Recklinghausen disease related protein VRNF, VRNF, WATS, Watson disease related protein WSS, Watson syndrome, WSS.

Background: Neurofibromin is a product of the tumor suppressor gene, Neurofibromatosis type I. Neurofibromin is known to have GTPase activity that modulates the ras pathway. The absence of or alteration of the neurofibromin protein may lead to Neurofibromatosis disease. This protein has not been purified, therefore, most of the information regarding this protein has been deduced from homology analysis of its gene sequence.

ID gène: 4763

Pathways: cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity