DPP4 anticorps (AA 473-588)

N° du produit ABIN7149984

L’anticorps Lapin Polyclonal anti-DPP4 a été validé pour WB, IHC, IF et ELISA. Il convient pour détecter DPP4 dans des échantillons de Humain.

Aperçu rapide pour DPP4 anticorps (AA 473-588) (ABIN7149984)

Antigène: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DPP4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Détail du produit anti-DPP4 anticorps

Épitope: AA 473-588

Fonction: DPP4 Antibody

Réactivité croisée: Rat

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Dipeptidyl peptidase 4 protein (473-588AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DPP4

Antigène: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Autre désignation: DPP4

Sujet:

Background: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

Aliases: ADABP antibody, ADCP-2 antibody, ADCP2 antibody, Adenosine deaminase complexing protein 2 antibody, CD26 antibody, Dipeptidyl peptidase 4 antibody, Dipeptidyl peptidase 4 soluble form antibody, Dipeptidyl peptidase IV antibody, Dipeptidyl peptidase IV membrane form antibody, Dipeptidyl peptidase IV soluble form antibody, DPP IV antibody, DPP4 antibody, DPP4_HUMAN antibody, DPPIV antibody, T-cell activation antigen CD26 antibody, TP103 antibody

UniProt: P27487

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity