DDR2 anticorps (AA 447-540)

N° du produit ABIN7150025

Détail du produit anti-DDR2 anticorps

Antigène: DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

Épitope: AA 447-540

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDR2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Discoidin domain-containing receptor 2 protein (447-540AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DDR2

Antigène: DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

Autre désignation: DDR2 (DDR2 Produits)

Synonymes: anticorps MIG20a, anticorps NTRKR3, anticorps TKT, anticorps TYRO10, anticorps AW495251, anticorps Ntrkr3, anticorps tyro10, anticorps DDR2, anticorps Tyro10, anticorps ddr2, anticorps si:ch211-193c2.1, anticorps discoidin domain receptor tyrosine kinase 2, anticorps discoidin domain receptor family, member 2, anticorps discoidin domain receptor family, member 2, like, anticorps DDR2, anticorps Ddr2, anticorps ddr2l

Sujet:

Background: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.

Aliases: CD167 antigen-like family member B antibody, CD167b antibody, CD167b antigen antibody, Cell migration inducing protein 20 antibody, DDR 2 antibody, DDR2 antibody, DDR2_HUMAN antibody, Discoidin domain containing receptor 2 antibody, Discoidin domain receptor 2 antibody, Discoidin domain receptor family member 2 antibody, discoidin domain receptor tyrosine kinase 2 antibody, Discoidin domain-containing receptor 2 antibody, discoidin domain-containing receptor tyrosine kinase 2 antibody, Hydroxyaryl protein kinase antibody, MIG20a antibody, Migration inducing gene 16 protein antibody, Neurotrophic tyrosine kinase antibody, Neurotrophic tyrosine kinase receptor related 3 antibody, NTRKR 3 antibody, NTRKR3 antibody, Receptor protein tyrosine kinase TKT antibody, Receptor protein-tyrosine kinase TKT antibody, Receptor related 3 antibody, receptor-related 3 antibody, TKT antibody, TYRO 10 antibody, TYRO10 antibody, Tyrosine kinase receptor related to neurotrophic TRK antibody, Tyrosine protein kinase TYRO 10 antibody, Tyrosine protein kinase TYRO10 antibody, Tyrosine-protein kinase TYRO10 antibody, Tyrosylprotein kinase antibody

UniProt: Q16832

Pathways: Signalisation RTK