POLH anticorps (AA 408-609)

N° du produit ABIN7150247

Cet anticorps Lapin Polyclonal détecte spécifiquement POLH dans WB, ELISA, IF et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour POLH anticorps (AA 408-609) (ABIN7150247)

Antigène: POLH (Polymerase (DNA Directed), eta (POLH))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLH est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-POLH anticorps

Épitope: AA 408-609

Fonction: POLH Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human DNA polymerase eta protein (408-609AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur POLH

Antigène: POLH (Polymerase (DNA Directed), eta (POLH))

Autre désignation: POLH

Sujet:

Background: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5\\\'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.

Aliases: DNA polymerase eta antibody, FLJ16395 antibody, FLJ21978 antibody, Polh antibody, POLH_HUMAN antibody, polymerase DNA directed eta antibody, RAD30 antibody, RAD30 homolog A antibody, RAD30A antibody, Xeroderma pigmentosum variant type protein antibody, XP V antibody, XPV antibody

UniProt: Q9Y253

Pathways: Réparation de l'ADN