TOPBP1 anticorps (AA 1253-1522)

N° du produit ABIN7150350

L’anticorps Lapin Polyclonal anti-TOPBP1 a été validé pour IHC et ELISA. Il convient pour détecter TOPBP1 dans des échantillons de Humain.

Aperçu rapide pour TOPBP1 anticorps (AA 1253-1522) (ABIN7150350)

Antigène: TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOPBP1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-TOPBP1 anticorps

Épitope: AA 1253-1522

Fonction: TOPBP1 Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human DNA topoisomerase 2-binding protein 1 protein (1253-1522AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TOPBP1

Antigène: TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))

Autre désignation: TOPBP1

Sujet:

Background: Required for DNA replication. Plays a role in the rescue of stalled replication forks and checkpoint control. Binds double-stranded DNA breaks and nicks as well as single-stranded DNA. Recruits the SWI/SNF chromatin remodeling complex to E2F1-responsive promoters. Down-regulates E2F1 activity and inhibits E2F1-dependent apoptosis during G1/S transition and after DNA damage. Induces a large increase in the kinase activity of ATR.

Aliases: DNA topoisomerase 2 binding protein 1 antibody, DNA topoisomerase 2-binding protein 1 antibody, DNA topoisomerase II binding protein 1 antibody, DNA topoisomerase II binding protein antibody, DNA topoisomerase II-beta-binding protein 1 antibody, DNA topoisomerase II-binding protein 1 antibody, DNA topoisomerase IIbeta binding protein 1 antibody, Hypothetical protein KIAA0259 [Fragment] antibody, KIAA0259 antibody, TOP2BP1 antibody, TOPB1_HUMAN antibody, TOPBP 1 antibody, TopBP1 antibody, Topoisomerase (DNA) II binding protein 1 antibody, Topoisomerase II binding protein 1 antibody

UniProt: Q92547

Pathways: Chromatin Binding