POLR2D anticorps (AA 1-142) (Biotin)

N° du produit ABIN7150435

Cet anticorps anti-POLR2D est un anticorps Lapin Polyclonal détectant POLR2D dans ELISA. Adapté pour Humain.

Aperçu rapide pour POLR2D anticorps (AA 1-142) (Biotin) (ABIN7150435)

Antigène: POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLR2D est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-POLR2D anticorps (Biotin)

Épitope: AA 1-142

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human DNA-directed RNA polymerase II subunit RPB4 protein (1-142AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur POLR2D

Antigène: POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))

Autre désignation: POLR2D

Sujet:

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA.

Aliases: DNA directed RNA polymerase II 16 kDa polypeptide antibody, DNA directed RNA polymerase II subunit D antibody, DNA directed RNA polymerase II subunit RPB4 antibody, DNA-directed RNA polymerase II 16 kDa polypeptide antibody, DNA-directed RNA polymerase II subunit D antibody, DNA-directed RNA polymerase II subunit rpb4 antibody, HSRBP4 antibody, HSRPB4 antibody, polr2d antibody, polymerase RNA II DNA directed polypeptide D antibody, RBP4 antibody, RNA polymerase II 16 kDa subunit antibody, RNA polymerase II subunit B4 antibody, RNA polymerase II subunit D antibody, RNA polymerase II subunit hsRBP4 antibody, RPB16 antibody, RPB4_HUMAN antibody

UniProt: O15514

Pathways: Regulatory RNA Pathways