Deltex Homolog 1 anticorps (AA 261-410) (Biotin)

N° du produit ABIN7151014

Détail du produit anti-Deltex Homolog 1 anticorps (Biotin)

Antigène: Deltex Homolog 1 (DTX1) (E3 Ubiquitin-protein ligase DTX1 (DTX1))

Épitope: AA 261-410

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Deltex Homolog 1 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human E3 ubiquitin-protein ligase DTX1 protein (261-410AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Deltex Homolog 1

Antigène: Deltex Homolog 1 (DTX1) (E3 Ubiquitin-protein ligase DTX1 (DTX1))

Autre désignation: DTX1 (DTX1 Produits)

Synonymes: anticorps hDx-1, anticorps Fxit1, anticorps mKIAA4160, anticorps deltex, anticorps dtx, anticorps xdtx1, anticorps deltex E3 ubiquitin ligase 1, anticorps deltex homolog 1 (Drosophila), anticorps deltex 1, E3 ubiquitin ligase, anticorps deltex 1 L homeolog, anticorps deltex 1 S homeolog, anticorps DTX1, anticorps dtx1, anticorps Dtx1, anticorps dtx1.L, anticorps dtx1.S

Sujet:

Background: Functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, suggesting that it can antagonize NOTCH1.

Aliases: Deltex 1, E3 ubiquitin ligase antibody, Deltex antibody, Deltex homolog 1 (Drosophila) antibody, Deltex homolog 1 antibody, Deltex protein 1 antibody, Deltex-1 antibody, Deltex1 antibody, dtx1 antibody, DTX1_HUMAN antibody, E3 ubiquitin protein ligase DTX1 antibody, E3 ubiquitin-protein ligase DTX1 antibody, FXI-T1 antibody, Fxit 1 antibody, Fxit1 antibody, hDTX1 antibody, hDx 1 antibody, mDTX1 antibody, Protein deltex 1 antibody, Protein deltex-1 antibody

UniProt: Q86Y01

Pathways: Signalisation Notch