RNF128 anticorps (AA 229-400) (Biotin)

N° du produit ABIN7151139

L’anticorps Lapin Polyclonal anti-RNF128 a été validé pour ELISA. Il convient pour détecter RNF128 dans des échantillons de Humain.

Aperçu rapide pour RNF128 anticorps (AA 229-400) (Biotin) (ABIN7151139)

Antigène: RNF128 (Ring Finger Protein 128 (RNF128))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF128 est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-RNF128 anticorps (Biotin)

Épitope: AA 229-400

Fonction: RNF128 Antibody, Biotin conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human E3 ubiquitin-protein ligase RNF128 protein (229-400AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RNF128

Antigène: RNF128 (Ring Finger Protein 128 (RNF128))

Autre désignation: RNF128

Sujet:

Background: E3 ubiquitin-protein ligase that catalyzes \'Lys-48\'- and \'Lys-63\'-linked polyubiquitin chains formation. Functions as an inhibitor of cytokine gene transcription. Inhibits IL2 and IL4 transcription, thereby playing an important role in the induction of the anergic phenotype, a long-term stable state of T-lymphocyte unresponsiveness to antigenic stimulation associated with the blockade of interleukin production. Ubiquitinates ARPC5 with \'Lys-48\' linkages and COR1A with \'Lys-63\' linkages leading to their degradation, down-regulation of these cytosleletal components results in impaired lamellipodium formation and reduced accumulation of F-actin at the immunological synapse. Functions in the patterning of the dorsal ectoderm, sensitizes ectoderm to respond to neural-inducing signals.

Aliases: E3 ubiquitin protein ligase RNF128 antibody, E3 ubiquitin-protein ligase RNF128 antibody, FLJ23516 antibody, Gene related to anergy in lymphocytes protein antibody, GRAIL antibody, RING finger protein 128 antibody, RN128_HUMAN antibody, RNF128 antibody

UniProt: Q8TEB7