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RNF139 anticorps (AA 510-664)

RNF139 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7151154
  • Antigène Voir toutes RNF139 Anticorps
    RNF139 (Ring Finger Protein 139 (RNF139))
    Épitope
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 510-664
    Reactivité
    • 18
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 28
    • 3
    • 1
    Lapin
    Clonalité
    • 30
    • 2
    Polyclonal
    Conjugué
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RNF139 est non-conjugé
    Application
    • 24
    • 13
    • 13
    • 9
    • 6
    • 4
    • 3
    ELISA, Immunohistochemistry (IHC)
     Réactivité croisée
    Humain
    Purification
    Antigen Affinity Purified
    Immunogène
    Recombinant Human E3 ubiquitin-protein ligase RNF139 protein (510-664AA)
    Isotype
    IgG
    Top Product
    Discover our top product RNF139 Anticorps primaire
  • Indications d'application
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    RNF139 (Ring Finger Protein 139 (RNF139))
    Autre désignation
    RNF139 (RNF139 Produits)
    Synonymes
    anticorps HRCA1, anticorps RCA1, anticorps TRC8, anticorps 4930555P18Rik, anticorps zgc:175173, anticorps rnf139, anticorps ring finger protein 139, anticorps ring finger protein 139 S homeolog, anticorps RNF139, anticorps Rnf139, anticorps rnf139, anticorps rnf139.S
    Sujet

    Background: E3-ubiquitin ligase, acts as a negative regulator of the cell proliferation through mechanisms involving G2/M arrest and cell death. Required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER). Affects SREBP processing by hindering the SREBP/SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression. Required for INSIG1 ubiquitination. May be required for EIF3 complex ubiquitination. May function as a signaling receptor.

    Aliases: RNF139 antibody, TRC8 antibody, E3 ubiquitin-protein ligase RNF139 antibody, EC 2.3.2.27 antibody, RING finger protein 139 antibody, RING-type E3 ubiquitin transferase RNF139 antibody, Translocation in renal carcinoma on chromosome 8 protein antibody

    UniProt
    Q8WU17
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