RNF43 anticorps (AA 566-697)

N° du produit ABIN7151198

Cet anticorps Lapin Polyclonal détecte spécifiquement RNF43 dans ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour RNF43 anticorps (AA 566-697) (ABIN7151198)

Antigène: RNF43 (Ring Finger Protein 43 (RNF43))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF43 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-RNF43 anticorps

Épitope: AA 566-697

Fonction: RNF43 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human E3 ubiquitin-protein ligase RNF43 protein (566-697AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RNF43

Antigène: RNF43 (Ring Finger Protein 43 (RNF43))

Autre désignation: RNF43

Sujet:

Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.

Aliases: RNF43 antibody, E3 ubiquitin-protein ligase RNF43 antibody, EC 2.3.2.27 antibody, RING finger protein 43 antibody, RING-type E3 ubiquitin transferase RNF43 antibody

UniProt: Q68DV7

Pathways: Signalisation WNT