ZNRF3 anticorps (AA 56-219) (Biotin)

N° du produit ABIN7151319

L’anticorps Lapin Polyclonal anti-ZNRF3 a été validé pour ELISA. Il convient pour détecter ZNRF3 dans des échantillons de Humain.

Aperçu rapide pour ZNRF3 anticorps (AA 56-219) (Biotin) (ABIN7151319)

Antigène: ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNRF3 est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-ZNRF3 anticorps (Biotin)

Épitope: AA 56-219

Fonction: ZNRF3 Antibody, Biotin conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human E3 ubiquitin-protein ligase ZNRF3 protein (56-219AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ZNRF3

Antigène: ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))

Autre désignation: ZNRF3

Sujet:

Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.

Aliases: ZNRF3 antibody, KIAA1133 antibody, RNF203 antibody, E3 ubiquitin-protein ligase ZNRF3 antibody, EC 2.3.2.27 antibody, RING finger protein 203 antibody, RING-type E3 ubiquitin transferase ZNRF3 antibody, Zinc/RING finger protein 3 antibody

UniProt: Q9ULT6

Pathways: Signalisation WNT