Emerin anticorps (AA 1-222)
Aperçu rapide pour Emerin anticorps (AA 1-222) (ABIN7151606)
Antigène
Voir toutes Emerin (EMD) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-222
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Réactivité croisée
- Humain, Souris
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human Emerin protein (1-222AA)
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Isotype
- IgG
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Indications d'application
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200, IP:1:200-1:2000,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Emerin (EMD)
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Autre désignation
- EMD
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Sujet
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Background: Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.
Aliases: EDMD antibody, Emd antibody, EMD_HUMAN antibody, Emerin antibody, Emery Dreifuss muscular dystrophy antibody, STA antibody
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UniProt
- P50402
Antigène
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