NGEF anticorps (AA 495-710) (FITC)

N° du produit ABIN7151825

Cet anticorps Lapin Polyclonal détecte spécifiquement NGEF dans . Il présente une réactivité envers Humain.

Aperçu rapide pour NGEF anticorps (AA 495-710) (FITC) (ABIN7151825)

Antigène: NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NGEF est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Détail du produit anti-NGEF anticorps (FITC)

Épitope: AA 495-710

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Ephexin-1 protein (495-710AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NGEF

Antigène: NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))

Autre désignation: NGEF

Sujet:

Background: Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).

Aliases: ARHGEF27 antibody, Eph receptor-interacting exchange protein antibody, Eph-interacting exchange protein antibody, EPHEXIN antibody, Ephexin-1 antibody, Guanine nucleotide exchange factor, neuronal antibody, Neuronal guanine nucleotide exchange factor antibody, Ngef antibody, NGEF_HUMAN antibody

UniProt: Q8N5V2

Pathways: Neurotrophin Signaling Pathway