EPH Receptor A5 anticorps (AA 246-514) (FITC)

N° du produit ABIN7151845

Cet anticorps anti-EPH Receptor A5 est un anticorps Lapin Polyclonal détectant EPH Receptor A5 dans . Adapté pour Humain.

Aperçu rapide pour EPH Receptor A5 anticorps (AA 246-514) (FITC) (ABIN7151845)

Antigène: EPH Receptor A5 (EPHA5)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor A5 est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Détail du produit anti-EPH Receptor A5 anticorps (FITC)

Épitope: AA 246-514

Fonction: EPHA5 Antibody, FITC conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Ephrin type-A receptor 5 protein (246-514AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur EPH Receptor A5

Antigène: EPH Receptor A5 (EPHA5)

Autre désignation: EPHA5

Sujet:

Background: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion (By similarity).

Aliases: Brain-specific kinase antibody, bsk antibody, CEK 7 antibody, Eck like sequence 1 antibody, EHK 1 antibody, EHK-1 antibody, EK7 antibody, Els 1 antibody, EPH homology kinase 1 antibody, EPH-like kinase 7 antibody, EPHA5 antibody, EPHA5_HUMAN antibody, Ephrin type A receptor 5 antibody, Ephrin type-A receptor 5 antibody, HEK 7 antibody, hEK7 antibody, Receptor protein tyrosine kinase HEK 7 antibody, Rek 7 antibody, TYRO 4 antibody, Tyrosine protein kinase receptor EHK 1 antibody

UniProt: P54756

Pathways: Signalisation RTK