EPH Receptor B3 anticorps (AA 261-390) (Biotin)

N° du produit ABIN7151865

L’anticorps Lapin Polyclonal anti-EPH Receptor B3 a été validé pour ELISA. Il convient pour détecter EPH Receptor B3 dans des échantillons de Humain.

Aperçu rapide pour EPH Receptor B3 anticorps (AA 261-390) (Biotin) (ABIN7151865)

Antigène: EPH Receptor B3 (EPHB3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor B3 est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-EPH Receptor B3 anticorps (Biotin)

Épitope: AA 261-390

Fonction: EPHB3 Antibody, Biotin conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Ephrin type-B receptor 3 protein (261-390AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur EPH Receptor B3

Antigène: EPH Receptor B3 (EPHB3)

Autre désignation: EPHB3

Sujet:

Background: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Generally has an overlapping and redundant function with EPHB2. Like EPHB2, functions in axon guidance during development regulating for instance the neurons forming the corpus callosum and the anterior commissure, 2 major interhemispheric connections between the temporal lobes of the cerebral cortex. In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses. Controls other aspects of development through regulation of cell migration and positioning. This includes angiogenesis, palate development and thymic epithelium development for instance. Forward and reverse signaling through the EFNB2/EPHB3 complex also regulate migration and adhesion of cells that tubularize the urethra and septate the cloaca. Finally, plays an important role in intestinal epithelium differentiation segregating progenitor from differentiated cells in the crypt.

Aliases: Cek10 antibody, EK2 antibody, Embryonic kinase 2 antibody, EPH Like Tyrosine Kinase 2 antibody, EPH receptor B3 antibody, EPH-like kinase 2 antibody, ephb3 antibody, EPHB3_HUMAN antibody, Ephrin receptor EphB3 antibody, Ephrin type B receptor 3 antibody, Ephrin type-B receptor 3 antibody, ETK2 antibody, hEK2 antibody, Human Embryo Kinase 2 antibody, Mdk5 antibody, Sek4 antibody, TYRO6 antibody, Tyrosine protein kinase receptor HEK2 antibody, Tyrosine protein kinase TYRO6 antibody, Tyrosine-protein kinase TYRO6 antibody

UniProt: P54753

Pathways: Signalisation RTK