EPH Receptor B4 anticorps (AA 300-540)

N° du produit ABIN7151868

L’anticorps Lapin Polyclonal anti-EPH Receptor B4 a été validé pour WB, ELISA et IHC. Il convient pour détecter EPH Receptor B4 dans des échantillons de Humain.

Aperçu rapide pour EPH Receptor B4 anticorps (AA 300-540) (ABIN7151868)

Antigène: EPH Receptor B4 (EPHB4)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor B4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-EPH Receptor B4 anticorps

Épitope: AA 300-540

Fonction: EPHB4 Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Ephrin type-B receptor 4 protein (300-540AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur EPH Receptor B4

Antigène: EPH Receptor B4 (EPHB4)

Autre désignation: EPHB4

Sujet:

Background: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.

Aliases: Ephb4 antibody, EPHB4_HUMAN antibody, Ephrin receptor EphB4 antibody, Ephrin type-B receptor 4 antibody, Hepatoma Transmembrane Kinase antibody, HTK antibody, MYK 1 antibody, MYK1 antibody, TYRO 11 antibody, TYRO11 antibody, Tyrosine-protein kinase receptor HTK antibody, Tyrosine-protein kinase TYRO11 antibody

UniProt: P54760

Pathways: Signalisation RTK