Ephrin B2 anticorps (AA 28-229)

N° du produit ABIN7151879

Cet anticorps Lapin Polyclonal détecte spécifiquement Ephrin B2 dans WB, IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Ephrin B2 anticorps (AA 28-229) (ABIN7151879)

Antigène: Ephrin B2 (EFNB2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ephrin B2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Ephrin B2 anticorps

Épitope: AA 28-229

Fonction: EFNB2 Antibody

Réactivité croisée: Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Ephrin-B2 protein (28-229AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Ephrin B2

Antigène: Ephrin B2 (EFNB2)

Autre désignation: EFNB2

Sujet:

Background: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.

Aliases: EFN B2 antibody, EFNB 2 antibody, Efnb2 antibody, EFNB2_HUMAN antibody, Eph related receptor tyrosine kinase ligand 5 antibody, EPH-related receptor tyrosine kinase ligand 5 antibody, ephrin B2 antibody, Ephrin-B2 antibody, EphrinB2 antibody, EPLG 5 antibody, EPLG5 antibody, Htk L antibody, HTK ligand antibody, HTK-L antibody, HTKL antibody, LERK 5 antibody, LERK-5 antibody, LERK5 antibody, Ligand of eph related kinase 5 antibody, MGC126226 antibody, MGC126227 antibody, MGC126228 antibody, OTTMUSP00000024973 antibody

UniProt: P52799

Pathways: Signalisation RTK, Regulation of Muscle Cell Differentiation