ERO1L anticorps (AA 24-260)

N° du produit ABIN7152002

Cet anticorps Lapin Polyclonal détecte spécifiquement ERO1L dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour ERO1L anticorps (AA 24-260) (ABIN7152002)

Antigène: ERO1L (ERO1-Like Protein alpha (ERO1L))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERO1L est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-ERO1L anticorps

Épitope: AA 24-260

Fonction: ERO1A Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human ERO1-like protein alpha protein (24-260AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ERO1L

Antigène: ERO1L (ERO1-Like Protein alpha (ERO1L))

Autre désignation: ERO1A

Sujet:

Background: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins. Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin. Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1.

Aliases: Endoplasmic oxidoreductin 1 like protein antibody, Endoplasmic oxidoreductin-1-like protein antibody, Endoplasmic reticulum oxidoreductase 1 alpha antibody, Endoplasmic reticulum oxidoreductin 1-like antibody, ERO1 alpha antibody, ERO1 L antibody, ERO1 Lalpha antibody, ERO1 like protein alpha antibody, ERO1-alpha antibody, ERO1-L antibody, ERO1-L-alpha antibody, ERO1-like (S. cerevisiae) antibody, ERO1-like alpha antibody, ERO1-like protein alpha antibody, ERO1-like, S. cerevisiae, homolog of, alpha antibody, ERO1A antibody, ERO1A_HUMAN antibody, ERO1L antibody, ERO1LA antibody, Oxidoreductin 1 Lalpha antibody, Oxidoreductin-1-L-alpha antibody, PRO865 antibody, UNQ434 antibody

UniProt: Q96HE7

Pathways: Peptide Hormone Metabolism, ER-Nucleus Signaling, Brown Fat Cell Differentiation