Exonuclease 1 anticorps (AA 301-600)

N° du produit ABIN7152265

Détail du produit anti-Exonuclease 1 anticorps

Antigène: Exonuclease 1 (EXO1)

Épitope: AA 301-600

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Exonuclease 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Exonuclease 1 protein (301-600AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Exonuclease 1

Antigène: Exonuclease 1 (EXO1)

Autre désignation: EXO1 (EXO1 Produits)

Synonymes: anticorps HEX1, anticorps hExoI, anticorps 5730442G03Rik, anticorps Msa, anticorps EXO1, anticorps exoi, anticorps fc16e04, anticorps wu:fc16e04, anticorps zgc:55521, anticorps exonuclease 1, anticorps hypothetical protein, anticorps exonuclease I Exo1, anticorps RNA exonuclease, anticorps exonuclease 1 S homeolog, anticorps EXO1, anticorps Y17G7B.12, anticorps SJAG_01832, anticorps PAS_chr1-1_0377, anticorps Exo1, anticorps exo1, anticorps exo1.S, anticorps LOC100338764

Sujet:

Background: 5\'->3\' double-stranded DNA exonuclease which may also possess a cryptic 3\'->5\' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5\' or 3\' to the mismatch. Also exhibits endonuclease activity against 5\'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5\'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.

Aliases: exo1 antibody, EXO1_HUMAN antibody, ExoI antibody, Exonuclease 1 antibody, Exonuclease I antibody, Exonuclease1 antibody, HEX1 antibody, hExo I antibody, hExo1 antibody, hExoI antibody, Rad2 nuclease family member homolog of S. cerevisiae exonuclease 1 antibody

UniProt: Q9UQ84

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response