EYA2 anticorps (AA 1-514)

N° du produit ABIN7152359

Cet anticorps Lapin Polyclonal détecte spécifiquement EYA2 dans ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour EYA2 anticorps (AA 1-514) (ABIN7152359)

Antigène: EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EYA2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-EYA2 anticorps

Épitope: AA 1-514

Fonction: EYA2 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Eyes absent homolog 2 protein (1-514AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur EYA2

Antigène: EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))

Autre désignation: EYA2

Sujet:

Background: Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2, in this it is functionally redundant with EYA1.

Aliases: EAB 1 antibody, EAB1 antibody, EYA 2 antibody, EYA transcriptional coactivator and phosphatase 2 antibody, EYA2 antibody, EYA2_HUMAN antibody, eyes absent 2 homolog (Drosophila) antibody, Eyes absent homolog 2 (Drosophila) antibody, Eyes absent homolog 2 antibody, Translation of this uORF probably lowers the translation efficiency of EYA2 antibody

UniProt: O00167