Fibrinogen beta Chain anticorps (AA 346-465)

N° du produit ABIN7152759

L’anticorps Lapin Polyclonal anti-Fibrinogen beta Chain a été validé pour IHC et ELISA. Il convient pour détecter Fibrinogen beta Chain dans des échantillons de Humain.

Aperçu rapide pour Fibrinogen beta Chain anticorps (AA 346-465) (ABIN7152759)

Antigène: Fibrinogen beta Chain (FGB)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fibrinogen beta Chain est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-Fibrinogen beta Chain anticorps

Épitope: AA 346-465

Fonction: FGB Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Fibrinogen beta chain protein (346-465AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Fibrinogen beta Chain

Antigène: Fibrinogen beta Chain (FGB)

Autre désignation: FGB

Sujet:

Background: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

Aliases: Beta fibrinogen antibody, Epididymis Secretory Sperm Binding Protein Li 78p antibody, FGB antibody, FIBB_HUMAN antibody, Fibrinogen beta chain antibody, Fibrinogen, B Beta Polypeptide antibody, HEL-S-78p antibody

UniProt: P02675