FCN1 anticorps (AA 30-326)

N° du produit ABIN7152931

Détail du produit anti-FCN1 anticorps

Antigène: FCN1 (Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1))

Épitope: AA 30-326

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FCN1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Ficolin-1 protein (30-326AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur FCN1

Antigène: FCN1 (Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1))

Autre désignation: FCN1 (FCN1 Produits)

Synonymes: anticorps FCNM, anticorps FCNB, anticorps FCN2, anticorps FCN1, anticorps ficolin 1, anticorps ficolin (collagen/fibrinogen domain containing) 1, anticorps ficolin-1, anticorps FCN1, anticorps Fcn1, anticorps LOC100069029

Sujet:

Background: Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8 (PubMed:21037097). Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.

Aliases: Collagen/fibrinogen domain containing protein 1 antibody, Collagen/fibrinogen domain-containing protein 1 antibody, Fcn1 antibody, FCN1_HUMAN antibody, FCNM antibody, ficolin (collagen/fibrinogen domain containing) 1 antibody, Ficolin 1 antibody, Ficolin A antibody, Ficolin alpha antibody, Ficolin-1 antibody, Ficolin-A antibody, Ficolin-alpha antibody, M ficolin antibody, M-ficolin antibody

UniProt: O00602

Pathways: Système du Complément